Question

A type of fish poisoning named for the Scombroid family is caused by eating fish with high amounts of this compound. For 10 points each:
[10m] Name this biogenic amine that is responsible for allergic reactions. Zyrtec and Allegra are examples of a class of drugs that block the receptor for this compound.
ANSWER: histamine [accept antihistamines]
[10h] Histamine is released by these immune cells which, like basophils, contain Fc-epsilon-RI receptors that bind to the antibody IgE (“I-G-E”) to trigger an allergic reaction.
ANSWER: mast cells
[10e] The degranulation of histamine-containing mast cells due to the binding of IgE antibodies stimulates this immune process which causes areas of the body to become hot, red, and swollen.
ANSWER: inflammation
<Science - Biology>

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